Boronic acid, B-(6-propoxy-3-pyridinyl)-
(6-Propoxypyridin-3-yl)boronic acid
CAS: 1150114-50-3
Molecular Formula: C8H12BNO3
Boronic acid, B-(6-propoxy-3-pyridinyl)- - Names and Identifiers
Boronic acid, B-(6-propoxy-3-pyridinyl)- - Physico-chemical Properties
| Molecular Formula | C8H12BNO3 |
| Molar Mass | 181 |
| Density | 1.16±0.1 g/cm3(Predicted) |
| Boling Point | 333.5±52.0 °C(Predicted) |
| pKa | 7.02±0.17(Predicted) |
| Storage Condition | 2-8°C |
| Sensitive | IRRITANT |
| MDL | MFCD11855844 |
Boronic acid, B-(6-propoxy-3-pyridinyl)- - Introduction
(6-Propoxypyridin-3-yl)boronic acid, also known as (6-Propoxypyridin-3-yl)boronic acid, is a chemical substance with the following properties:
Nature:
-Appearance: colorless or yellowish crystal powder
-Molecular formula: C10H13BNO3
-Molecular weight: 207.03g/mol
-Melting point: 140-145 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, chloroform, etc.
Use:
(6-Propoxypyridin-3-yl)boronic acid is an organic boron compound with a wide range of applications in the field of organic synthesis:
-As a coordinating reagent: It can form complexes with anions or metals, and plays an important role in metal-catalyzed reactions.
-As an intermediate in organic synthesis: It can be used to synthesize compounds containing benzene ring or pyridine ring, such as drugs, pesticides, etc.
-Used to construct carbon-carbon, carbon-oxygen and carbon-nitrogen bonds: can participate in a variety of important reactions, such as the coupling reaction of boronic acid and aromatic ketones.
Preparation Method:
(6-Propoxypyridin-3-yl) There are many preparation methods for boronic acid. One commonly used method is:
3-Pyridinemethanol and 6-iodo-substituted brominated alkane are reacted under basic conditions to produce (6-iodopyridin-3-yl) methanol.
Then (6-iodopyridin-3-yl) methanol is reacted with boric acid or boric acid ester under basic conditions to produce the final product (6-Propoxypyridin-3-yl)boronic acid.
Safety Information:
(6-Propoxypyridin-3-yl)boronic acid belongs to chemicals, and corresponding safety regulations shall be observed during operation:
-Irritation: Contact with skin and eyes may cause irritation, direct contact should be avoided.
-Inhalation risk: It can enter the body through the respiratory tract, and inhalation of dust should be avoided.
-physical properties: with a certain degree of combustion, should be away from the source of fire.
-Storage and handling: should be stored in a dry, ventilated place, avoid contact with oxidants and acids and other substances.
Nature:
-Appearance: colorless or yellowish crystal powder
-Molecular formula: C10H13BNO3
-Molecular weight: 207.03g/mol
-Melting point: 140-145 degrees Celsius
-Solubility: Slightly soluble in water, soluble in organic solvents such as ethanol, chloroform, etc.
Use:
(6-Propoxypyridin-3-yl)boronic acid is an organic boron compound with a wide range of applications in the field of organic synthesis:
-As a coordinating reagent: It can form complexes with anions or metals, and plays an important role in metal-catalyzed reactions.
-As an intermediate in organic synthesis: It can be used to synthesize compounds containing benzene ring or pyridine ring, such as drugs, pesticides, etc.
-Used to construct carbon-carbon, carbon-oxygen and carbon-nitrogen bonds: can participate in a variety of important reactions, such as the coupling reaction of boronic acid and aromatic ketones.
Preparation Method:
(6-Propoxypyridin-3-yl) There are many preparation methods for boronic acid. One commonly used method is:
3-Pyridinemethanol and 6-iodo-substituted brominated alkane are reacted under basic conditions to produce (6-iodopyridin-3-yl) methanol.
Then (6-iodopyridin-3-yl) methanol is reacted with boric acid or boric acid ester under basic conditions to produce the final product (6-Propoxypyridin-3-yl)boronic acid.
Safety Information:
(6-Propoxypyridin-3-yl)boronic acid belongs to chemicals, and corresponding safety regulations shall be observed during operation:
-Irritation: Contact with skin and eyes may cause irritation, direct contact should be avoided.
-Inhalation risk: It can enter the body through the respiratory tract, and inhalation of dust should be avoided.
-physical properties: with a certain degree of combustion, should be away from the source of fire.
-Storage and handling: should be stored in a dry, ventilated place, avoid contact with oxidants and acids and other substances.
Last Update：2024-04-09 02:00:57
